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However, the beneficial effect was not replicated in the larger and more stringently performed phase III EMBODY trial (25)

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FIGURE 2 7.1.2 Reducing systemic inflammation Patients with pulmonary function impairment often experience systemic inflammation, which not only further affects lung function but can also lead to other complications (Sungurlu and Balk, 2024), while promoting the release of anti-inflammatory cytokine IL-10 to help reduce the inflammatory response (Sleijser-Koehorst et al., 2023